• Married for 22 years
• Primary Infertility
• 3 IUI Failed
• 3 IVF Failed
• 4th IVF: Problem in fetal growth
• Elevated levels of cytokines and NK cells
Assisted Reproductive Technology (ART)
• Immunomodulation therapy given
• Downregulation of cytokines and NK cells achieved
•
Delivered healthy twins (One male, one female)
INFERTILITY: CASE 2
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
30 Years/ Female
• Married for 10 years
• Primary Infertility
• 4 IUI failed
• 4 IVF failed
Natural Pregnancy
• Endometrial receptivity low
• Immunomodulation therapy given
• Enhancement of endometrial receptivity
• Delivered twin female babies
INFERTILITY: CASE 3
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
35 Years/ Female
• Married for 14 years
• Primary Infertility
• 7-8 IUI failed
• Elevated levels of cytokines and NK cells
Assisted Reproductive Technology (ART)
• Immunomodulation therapy given
• Downregulation of cytokines and NK cells achieved
• Delivered healthy female baby
INFERTILITY: CASE 4
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
39 Years/ Female
• Married for 16 years
• Primary Infertility
• 1 IUI failed
• 1 IVF failed
Assisted Reproductive Technology (ART)
• Immunomodulation therapy given
• Delivered healthy male baby
RECURRENT PREGNANCY LOSS: CASE 1
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
26 Years/ Female
• Married for 7 years
• 9 miscarriages
• 1 IUI failed
• 1 IVF failed
• Elevated levels of cytokines and NK cells
Natural Pregnancy
• Immuomodulation therapy given
• Downregulation of cytokines and NK cells achieved
• Delivered a healthy baby
RECURRENT PREGNANCY LOSS: CASE 2
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
32 Years/ Female
• Married for 8 years
• 8 first Trimester abortions
• Elevated levels of NK cells
Natural Pregnancy
• Immunomodulation therapy given
• Downregulation of NK cells achieved
• Delivered a healthy baby
RECURRENT PREGNANCY LOSS: CASE 3
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
38 Years/ Female
• Married for 7 years
• 8 missed abortions
• Elevated levels of NK cells
Natural Pregnancy
• Immunomodulation therapy given
• Downregulation of NK cells achieved
• Delivered a healthy female baby
RECURRENT PREGNANCY LOSS: CASE 4
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
30 Years/ Female
• Married for 5 years
• 7 first trimester abortions
• Critical period during pregnancy: 6-7 weeks
Natural Pregnancy
• Immune modulation therapy given
• Delivered a healthy female baby
RECURRENT PREGNANCY LOSS: CASE 5
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
34 Years/ Female
• Married for 15 years
• 6 missed abortions
• Elevated Latent TB, cytokines and NK cells
Natural Pregnancy
• Immunomodulation therapy given
• Downregulation of Latent TB, cytokines and NK
cells achieved
• Delivered healthy male baby
RECURRENT PREGNANCY LOSS: CASE 6
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
32 Years/ Female
• Married for 12 years
• 6 first Trimester abortions
• Critical period during pregnancy: 7 weeks
• Elevated levels of cytokines and NK cells
Assisted Reproductive Technology (ART)
• Immunomodulation therapy given
• Downregulation of cytokines and NK cells achieved
• Delivered a healthy female baby
RECURRENT PREGNANCY LOSS: CASE 7
PATIENTS
PRE-INTERVENTION PATIENT STATUS
TYPE OF CONCEPTION
POST INTERVENTION
38 Years/ Female
• Married for 6 years
• Consanguinous marriage
• 5 abortions
• Elevated levels of cytokines and NK cells
Natural Pregnancy
• Immunomodulation therapy given
• Downregulation of cytokines and NK cells achieved
• Delivered healthy twin male babies
